Evaluation of Potentially Bioactive Foods With Respect to Cardiometabolic- and Cognitive Test Variables
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 17
- 试验地点
- 4
- 主要终点
- glucose tolerance
研究概览
简要总结
The overall goal is to increase the knowledge that can be used for the development of food products with anti-diabetic properties, with the purpose to facilitate healthier food choices for people. More specifically the primary purpose of this project is to evaluate effects in healthy humans on acute postprandial glucose regulation of plant based lipids. Due to the tight connection between cardiometabolic health and cognitive functions, a secondary issue is to investigate effects of test foods on cognitive test variables and mood parameters.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Apparently healthy subjects
- •Between 20 and 40 years old
- •Body mass index between 19-28 kg / m2),
- •Consuming a non-vegetarian diet generally in line with the Nordic nutrition recommendations.
排除标准
- •Fasting blood glucose concentration >6.1 mmol/L
- •Known metabolic or gastrointestinal disorder (eg diabetes, high cholesterol, high blood pressure, IBS), or other disease that may affect the study results.
- •Regular medication, except for long-term and stable medication for the lack or reduced production of thyroid hormone (eg Levaxin).
- •Antibiotics or probiotics for at least four weeks before the start of the study,
- •The use of tobacco products
结局指标
主要结局
glucose tolerance
时间窗: 3 hours. Fasting (time =0), 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes
Postprandial blood glucose responses
次要结局
- Insulin responses(3 hours. Fasting (time =0 minutes), 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes)
- Mood variables(60 minutes after start of test product, after 120 minutes and after 180 minutes)
- Appetite sensations(3 hours. Fasting (time =0), 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes)
研究者
Anne Nilsson
Associate professor
Lund University