NCT01323088已完成不适用
Physical Activity in Overweight Girls: Implications for Reversing Risk Factors for Type 2 Diabetes
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Abdominal obesity, visceral fat
研究概览
简要总结
In this randomized controlled trial, we will examine the effect of a 3-month exercise training (aerobic exercise versus resistance exercise) without calorie restriction on total and regional adiposity, ectopic fat in the liver and skeletal muscle, and risk of type 2 diabetes in overweight girls.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 12 Years 至 18 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Healthy overweight (BMI >-95th) youth between 12 and 18 years of age
- •Waist circumference >-75th percentile
- •Sedentary (no structured exercise >2 times/week for past 6 months)
- •Non-smokers, non-diabetic, no medical conditions
- •Weight stable for past 3 months
排除标准
- •Psychiatric disorders
- •Syndromic obesity
- •Pregnancy
- •Taking medications known to affect study outcomes
结局指标
主要结局
Abdominal obesity, visceral fat
时间窗: 3 month
次要结局
- insulin sensitivity by a 3-hour hyperinsulinemic-euglycemic clamp, oral glucose tolerance test, liver fat and intramyocellular lipid by 1H-magnetic resonance spectroscopy.(3 month)
研究者
研究点 (1)
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