Comparison between intravenous Dexamethasone and intravenous Ondansetron for prevention of post spinal hypotension in patients undergoing elective lower segment caesarean section : A randomized controlled trial

Sub arachnoid block is the preferred anaesthesia for elective LSCS as it has better maternal and fetal outcome as compared to general anaesthesia. Most common side effect of spinal anaesthesia is post spinal hypotension with an incidence ranging from 50 to 80 % in patients undergoing LSCS. Post spinal hypotension can lead to serious maternal as well as fetal compromise due to reduced umbillical blood flow prior to delivery. Hence it is necessary to address this condition. Various pharmacological and non pharmacological agents have been tried to prevent and treat post spinal hypotension with varying degrees of effectiveness. Dexamethasone is relatively newer agent and it has shown promising outcome in preventing post spinal hypotension during LSCS. But its exact efficacy is yet to be proven . Ondansetron is an established drug for prevention of post spinal hypotension. Therefore our study aims to compare the efficacy of intravenous Dexamethasone and Intravenous Ondansetron for prevention of post spinal hypotension in elective LSCS as Dexamethasone is comparatively safer alternative for pregnant women with respect to Ondansetron.