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临床试验/ISRCTN23677189
ISRCTN23677189已完成不适用

A study on the training response of combined strength and endurance training in insulin dependent type 2 diabetic subjects with co-morbidity

niversity Maastricht (UM) (Netherlands)0 个研究点目标入组 36 人开始时间: 2010年3月16日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
36

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
Male

入选标准

  • •Group A: long-term type 2 diabetes group (intervention group):
  • •2. Diagnosed with type 2 diabetes greater than 5 years according to World Health Organization (WHO) criteria
  • •3. Exogenous insulin use greater than 2 years
  • •4. Clinical signs of diabetic polyneuropathy and/or other diabetes-related
  • •5. Aged 45 - 70 years
  • •6. Body mass index (BMI) 26 - 42 kg/m^2
  • •7. Sedentary behaviour
  • •8. Agreement to volunteer for the study by giving a written informed consent
  • •Group B: intermediate hyperglycaemia group/early-diagnosed type 2 diabetes patients:
  • •2. Intermediate hyperglycemia according to WHO criteria
  • •3. HbA1c less than or equal to 6.0%
  • •4. Aged 45 - 70 years (matched with group A)
  • •5. BMI 26 - 42 kg/m^2 (matched with group A)
  • •6. Wmax (cycle ergometer): 100 - 220 Watt
  • •7. Sedentary behaviour
  • •8. Agreement to volunteer for the study by giving a written informed consent
  • •Group C: overweight/obese but otherwise healthy subjects with normal glucose tolerance:
  • •2. Normal glucose tolerance according to WHO criteria
  • •3. HbA1c less than or equal to 6.0%
  • •4. Aged 45 - 70 years
  • •5. BMI 26 - 42 kg/m^2 (matched with group A)
  • •6. Wmax: 100 - 220 Watt
  • •7. Sedentary behaviour
  • •8. Agreement to volunteer for the study by giving a written informed consent

排除标准

  • •1. Unable to participate in a structured exercise intervention for 12 months
  • •2. Use of thiazolidinions
  • •3. Use of beta-blocker therapy less than 6 months
  • •Group B and C:
  • •1. Family history of type 2 diabetes
  • •2. Use of beta-blocker therapy
  • •3. History/clinical signs of cardiovascular and/or peripheral arterial disease

研究者

发起方
niversity Maastricht (UM) (Netherlands)

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