Investigating Accelerated Learning and Memory in Healthy Subjects Using a Face Name Memory Task
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Associative Memory Assessed by a Face Name Associate Memory Experiment
研究概览
简要总结
The purpose of this study is to investigate whether we can accelerate learning and improve associative memory performance in healthy subjects by applying transcranial Direct Current Stimulation (tDCS) during a Face Name memory task.
详细描述
Associative memory refers to remembering the association between two items, such as a face and a name or a word in English and the same word in another language. It is not only important for learning, but it is also one of the first aspects of memory performance that is impacted by aging and by Alzheimer׳s disease. For decades, neuroscientists have investigated associative learning and memory and ways to accelerate and enhance associative learning and memory.
Transcranial Direct Current stimulation (tDCS) is a non-invasive and painless electrical stimulation technique that has demonstrated to accelerate learning and improve memory in some studies. To investigate whether we can accelerate learning and improve associative memory using tDCS, we will compare the performance in a Face Name Associate memory task from 2 groups. The first group will get active tDCS during the study phase of the Face Name Memory task, whereas the second group will get sham tDCS during the study phase of the task.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age: 18-35 years
- •Native English Speaker
排除标准
- •History of severe head injuries, epileptic insults, or heart disease.
- •Severe psychiatric disorders and severe untreated medical problems.
- •Contraindications for tDCS (pregnant women, implanted devices)
研究组 & 干预措施
active tDCS
active tDCS with Face Name associate Memory task
干预措施: tDCS (Device)
sham tDCS
sham tDCS with Face Name associate Memory task
干预措施: sham tDCS (Device)
结局指标
主要结局
Associative Memory Assessed by a Face Name Associate Memory Experiment
时间窗: Associate Memory is assessed after a 10 minutes break following the study phase
All participants performed a face memory task .The face stimuli consisted of 120 grayscale pictures of human faces. Only faces with a neutral expression facing forward were selected. Half of the faces were male, and the other half were female. The face-name association memory task was divided into (1) an encoding phase, (2) a consolidation phase, and (3) a retrieval phase. During the encoding phase, participants studied 60 successively presented face-name pairs and were instructed to assess their gender to keep them focused to the task. The encoding phase was followed by a consolidation phase where participants were instructed to "sit still, relax, and think about nothing in particular" for 10 minutes, During the retrieval phase, participants were presented with 60 old and 60 new faces and were instructed to assess whether they have seen this face during the encoding phase. The outcome was the percent of Correct Name to Face Matches
次要结局
未报告次要终点
研究者
Sven Vanneste
Associate professor
The University of Texas at Dallas