NCT00970827已完成2 期
Remote Ischemic Postconditioning During Percutaneous Coronary Interventions.
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 360
- 试验地点
- 2
- 主要终点
- Myocardial injury after PCI.
研究概览
简要总结
Angioplasty is a commonly performed procedure for treating blockage of the blood vessels in the heart. Although this procedure is usually successful, it is often accompanied by a small degree of damage to the heart (i.e., small heart attack).
The purpose of this study is to find out if inflating a blood pressure cuff on the arm or the leg at the time of angioplasty for several minutes has a beneficial effect.
Patients will be assigned to one of three treatment groups: inflating blood pressure cuff on the arm, inflating blood pressure cuff on the leg and a control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for PCI
排除标准
- •Acute myocardial infarction
- •Myocardial infarction or coronary bypass surgery during the last 4 weeks before PCI
- •Use of Glyburide
- •Heart failure (NYHA III/IV)
- •Chronic inflammatory disease
- •Severe renal impairment
- •Significant peripheral vascular disease
- •Unsuitable for use of an embolic protection device for PCI to SVG
结局指标
主要结局
Myocardial injury after PCI.
时间窗: 24 hours
次要结局
- To study the effects of different degrees of remote ischemic postconditioning on myocardial necrosis and inflammation following PCI.(24 hours)
- Platelet function(24 hours)
- Cardiac events(One year)
研究者
Shahar Lavi
Principal Investigator
Lawson Health Research Institute
研究点 (2)
Loading locations...
相似试验
Unknown
不适用
Chronic Remote Ischemic Conditioning to Modify Post-MI RemodelingMyocardial InfarctionNCT01817114The Hospital for Sick Children20
已完成
不适用
Application of Perioperative Remote Ischemic Conditioning in Patients Undergoing HepatectomyHepatolithiasisHepatectomyLiver CancerHepatic HemangiomaNCT06130436The Second Affiliated Hospital of Chongqing Medical University135
已完成
不适用
Post-conditioning to Reduce Infarct SizeMyocardial InfarctionNCT00755469Minneapolis Heart Institute Foundation43
已完成
不适用
The Effect of Remote Ischemic Postconditioning on Liver Graft and Renal Function in Patients Undergoing Living-related Liver TransplantationIschemia/Reperfusion Injury of Liver GraftIschemia/Reperfusion Injury of KidneyRemote Ischemic PostconditioningNCT01637038Samsung Medical Center80
已完成
不适用
Cutaneous Remote Ischemic Preconditioning in Plastic SurgeryIschemic PreconditioningNCT01235286Hannover Medical School27