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临床试验/NCT04108182
NCT04108182招募中不适用

A Registry Study of Biomarkers in Progression of Acute Heart Failure

Beijing Institute of Heart, Lung and Blood Vessel Diseases1 个研究点 分布在 1 个国家目标入组 850 人开始时间: 2015年12月最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
850
试验地点
1
主要终点
Number of death ( all cause) or readmission for heart failure

研究概览

简要总结

The registry study aims to discover the prognostic value of bio-markers in acute heart failure

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients aged greater than or equal to 18 years with acute exacerbation of chronic heart failure or new heart failure
  • With typical symptoms of acute heart failure as follows: Dyspnea, ankle swelling and fatigue (Limited activity endurance), increased jugular pressure, rales and peripheral edema ;
  • Plasma concentrations of BNP: BNP>100pg/ML
  • Echocardiography: Related structural heart disease (left ventricular hypertrophy and/or left atrial enlargement) and/or diastolic dysfunction

排除标准

  • Previous history of cancer or renal replacement therapy
  • 2.Surgery was performed within a month
  • 3.Accompanied by cardiogenic shock, sepsis, pneumonia
  • 4.Eligible patients without informed consent form

结局指标

主要结局

Number of death ( all cause) or readmission for heart failure

时间窗: a median follow-up of 8.8 months

Number of Death or heart failure related hospitalization within a median follow-up of 8.8 months of discharge

次要结局

  • Number of death ( all cause) or readmission for heart failure and cardiovascular mortality(a median follow-up of 8.8 months)

研究者

发起方
Beijing Institute of Heart, Lung and Blood Vessel Diseases
申办方类型
Other
责任方
Sponsor

研究点 (1)

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