The addition of clonidine to bupivacaine/adrenaline intercostal nerve blockades in patients undergoing open cholecystectomies - Intercostal clonidine

VO Anesthesia/ICU Lunds University Hospital0 个研究点开始时间: 2007年4月18日最近更新: 2012年3月19日

适应症

试验速览

暂无简介。

•·Patients with the diagnosis of cholelithiasis.
•·Patients fulfilling criteria for ASA (American Society of Anesthesiologists) classification 1-3; see appendix
•·Patients scheduled for either open cholecystectomies or reversed from laparoscopic to open cholecystectomies.
•·Signed informed consent by patient.
•·Age 18-75 years.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Preoperative exclusion criteria:
•·Chronic pain or ingestion of pain modulating drugs on a regular basis preoperatively.
•·Non-tolerance or contraindications to local anesthetics, clonidin, adrenalin or opioids.
•·Cognitive or linguistic problems precluding effective postoperative pain evaluation.
•·Patients with a body weight less than 50 kg or exceeding > 150 kg.
•·Dermatitis or infection overlying injection sites or anatomical reason contraindicating an intercostal blockade.
•·Chronic Obstructive Pulmonary Disease or other criteria which increase the risk of significant pneumothorax after intercostal blockade.
•Intraoperative exclusion criterias:
•·Planned laparoscopic surgery completed without conversion to open cholecystectomi.
•·Unforeseen complication of anesthetic management requiring prolonged intubation postoperatively.
•·Surgical complication with surgical time of > 2 hours, injuries to choledochus or spleen intraoperatively.
•·The need for intraabdominal or intrathoracal drainage postoperatively.

发起方

VO Anesthesia/ICU Lunds University Hospital