NCT06536998招募中不适用
Exploring the Association of Imaging and Tumor Microenvironment in Liver Cancer Using Radiogenomic Approach（Radiogenomics-Liver）
Wuhan Union Hospital, China1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2024年8月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Correlation analysis of sequencing results and body composition
研究概览
简要总结
This is the prospective, observational cohort study (Radiogenomics-Liver), which aims to explore the relationship between the imaging information of liver cancer patients, tumor microenvironment and the prognosis of liver cancer patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients treated for liver cancer in Wuhan Union Hospital from August 2024 to August 2027;
- •Aged > 18 years old;
- •At least one CT scan or MRI scan before treatment;
- •Tissue biopsy pathological examination confirmed the diagnosis of the above tumors.
- •Exclusion criteria：
- •Poor image quality;
- •Incomplete clinical data or loss of follow-up;
- •Presence of another primary malignancy other than liver cancer;
- •Unclear pathological diagnosis.
排除标准
- 未提供
结局指标
主要结局
Correlation analysis of sequencing results and body composition
时间窗: 0.5 year
Conducting correlation analysis between body composition and results of multi-omics sequencing
Correlation analysis of sequencing results and tumor radiomic features
时间窗: 0.5 year
Conducting correlation analysis between radiomic features and results of multi-omics sequencing
次要结局
- Constructing a multi-dimensional prognostic prediction model(3 years)
- Constructing tumor microenvironment prediction model(2 years)
研究者
研究点 (1)
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