A Cohort Study: to Assess the Value of Cardiovascular Imaging in Pediatric Myocarditis
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Adverse cardiovascular events
研究概览
简要总结
This study aims to utilize cardiac magnetic resonance (CMR) to assist in the clinical diagnosis, conduct consecutive assessments for myocardial tissue in pediatrics with myocarditis, and explore effective predictive factors for adverse outcomes in pediatric myocarditis.
Participants will undergo baseline collection, laboratory tests, echocardiography, and CMR. All the consecutive data will be used to analyze the association with the diagnosis and prognosis of pediatric myocarditis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients diagnosed or suspected pediatric myocarditis based on Diagnostic Recommendation for Myocarditis in Children (version 2018).
- •Age between 1 to 18 years old.
排除标准
- •Previous history of cardiovascular disease ( e.g. congenital heart disease, cardiomyopathy, rheumatic heart disease, valvular disease ).
- •MRI examination contraindications ;
- •Gadolinium contrast agent contraindications ;
- •CT examination contraindications ;
- •Comparison of iodine content.
结局指标
主要结局
Adverse cardiovascular events
时间窗: 10 years after the onset
including all-cause death, orthotopic heart transplantation(HTx), malignant arrhythmia, readmission due to heart failure, progression to DCM.
次要结局
- Secondary cardiovascular adverse events(10 years after the onset)
研究者
Ling-Yi Wen
Principal Investigator
West China Second University Hospital