The Relationship Between Morbid Obesity and Carotid Artery Stenosis - a Comparative Prospective Study
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 主要终点
- Correlation between morbid obesity and carotid artery stenosis
研究概览
简要总结
The correlation between metabolic syndrome and carotid artery stenosis is well established. The purpose of this study is to evaluate the relationship between morbid obesity and carotid artery stenosis.
详细描述
The investigators hypothesis is that there is a direct relationship between morbid obesity and carotid artery stenosis. The investigators hypothesize that metabolic/Bariatric surgery improves the stenosis in the carotid artery.
This is a prospective comparative study on the candidates for metabolic/Bariatric surgery in the bariatric center, Emek Medical Center, Afula, Israel. The investigators will compare the candidate for metabolic surgery with metabolic syndrome risk factors to the ones without metabolic syndrome risk factors.
The assessment of the carotid artery will be done by Ultrasound Doppler before surgery and 6, 12 and 24 month post surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Candidates for first bariatric surgery
排除标准
- •Smokers or past smokers
- •Patients who are post carotid artery intervention
结局指标
主要结局
Correlation between morbid obesity and carotid artery stenosis
时间窗: 24 months post surgery
Evaluate the correlation between the two in order to identify high risk patient for carotid stenosis without metabolic syndrome risk factors
次要结局
- Changes in Intimal -media thickness(Before bariatric surgery, and 6,12,24 months after the surgery)
- Changes in the carotid artery velocity(Before bariatric surgery, and 6,12,24 months after the surgery)
研究者
Uri Kaplan , MD
MD
HaEmek Medical Center, Israel