Distribution of blood eosinophils in patients with chronic obstructive pulmonary disease (COPD) living in areas of endemic helminth infections:a cross-sectional study in South East Asia (Helminth study)

Glaxo Smith Kline0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1.Male or female at least 40 years old
•2.Capable of giving written informed consent
•3.Have a prior diagnosis of COPD documented in the medical record
•4. Have COPD diagnosis confirmed by post-bronchodilator spirometry test at
•5. Have moderate-severe airflow limitation defined as a forced expiratory volume in
•one second (FEV1)/forced vital capacity (FVC) less than 0.7 and FEV1 less than
•80% predicted on post-bronchodilator spirometry at enrolment

•1. Onset of COPD symptoms before 30 years of age
•2. Experienced an acute exacerbation of COPD (defined as an acute worsening of
•symptoms that result in treatment with an antibiotic or oral steroid) within the
•four weeks prior to, or on the date of, enrolment
•3. Have diagnosed asthma over the past 12 months or have experienced asthma
•symptoms with a clinical history suggestive of asthma in the past 12 months
•4. Have cystic fibrosis, pulmonary fibrosis or bronchiectasis documented in the
•medical record
•5. Have active tuberculosis or are taking medication for tuberculosis
•6. Have had pulmonary resection surgery
•7. Are pregnant (women of childbearing potential with positive urine pregnancy test
•will be excluded)

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