Genetic vulnerability to stress across psychiatric diagnoses. Schizophrenia and Major Depressive Disorder - Stress and brain in psychiatry

niversitair Medisch Centrum Utrecht0 个研究点目标入组 90 人开始时间: 待定最近更新: 2024年5月13日

适应症

试验速览

暂无简介。

•Subjects have to satisfy the following criteria in order to participate in the study:
•- Give written informed consent
•- Aged between 18-65 years of age;Specific for schizophrenia patients:
•- Do have a DSM-IV diagnosis of Schizophrenia
•- Do not chronically use medication, other than psychiatric medication
•- Are not in an acute psychotic episode, but stable for at least 6 months;Specific for MDD patients:
•- Do have a DSM-IV diagnosis of Major Depressive Disorder
•- Do not chronically use medication, other than psychiatric medication
•- Are not in an acute depressive episode, but stable for at least 6 months
•- Have had at least two depressive episodes and at least one hospital admission due to affective symptoms

•- Ferrous objects in or around the body (e.g. braces, pacemaker, metal fragments)
•- Claustrophobia
•- Drug or alcohol abuse over a period of six months prior to the experiment
•- History of closed-head injury
•- History of neurological illness or endocrinological dysfunction
•- A pacemaker;Specific for the healthy individuals:
•- A psychiatric history
•- Chronic use of medication
•- A first-degree family member with a psychiatric illness

发起方

niversitair Medisch Centrum Utrecht