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临床试验/NL-OMON34510
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ature and mechanisms of cognitive deficits following chemotherapy: an (f)MRI study - chemotherapy, cognition and (f)MRI

Antoni van Leeuwenhoek Ziekenhuis0 个研究点目标入组 180 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
180

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • All groups:
  • -female, independent of menopausal status
  • -age under 70 years (to allow use of the same neuropsychological test battery)
  • -sufficient proficiency in the Dutch language;Experimental group:
  • -newly diagnosed breast cancer patients without distant metastases who will receive anthracycline-based chemotherapy ;Breast cancer control group:
  • -newly diagnosed breast cancer patients without distant metastases who do not require chemotherapy;Healthy control group:
  • -healthy females, matched for age

排除标准

  • All groups:
  • -previous malignancies
  • -excessive use of alcohol or drugs
  • -use of psychotropic medication
  • -neurologic or psychiatric disorders that may influence cognitive functioning
  • -conditions that preclude MRI examination.;Experimental group and breast cancer control group:
  • -relapse and/or metastases
  • - treatment with trastuzumab (Herceptin)

研究者

发起方
Antoni van Leeuwenhoek Ziekenhuis

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