TCTR20181119002终止未知
The role of childhood adversity in cortisol dysregulation in depressed and non-depressed methamphetamine users with and without history of suicide
none0 个研究点目标入组 195 人开始时间: 2018年11月19日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 终止
- 发起方
- 入组人数
- 195
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •(a) age of 18 to 65 years; (b) a history of at least two years of continuous consumption of methamphetamine by a vapor inhalation model about 0.5 to 1 g/day; (c) a diagnosis of drug dependence and MDD based on DSM-5 criteria and history of suicide attempt in the past or the existence of suicidal ideation in the last 12 months; (d) being in the abstinence phase for at least six and not more than 12 months and the presence of PAWS in the depressed group; (e) the history of suicide attempt at least once and at most three times; (f) body mass index (BMI) between 18 and 35 kg; and (g) lack of suicide attempts and suicidal ideation in the control group.
排除标准
- •(a) history of seizure, head trauma, endocrine disruptions, cardiovascular disease or other specific chronic diseases; (b) treatment in the last 6 months with antidepressants, neuroleptics, sedatives, glucocorticoids, appetite suppressants, estrogens, dopamine medications; (c) Experience of any extraordinary stress at present; and (d) pregnancy, hormone intake, or any cortisol simulants or suppressants. Money was paid to people for their contributions.
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