NCT00516711已完成不适用
Role of Volatile Anesthetics for Hepatic Protection in Ischemia-reperfusion
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 试验地点
- 1
- 主要终点
- Blood levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT)
研究概览
简要总结
This study aims to evaluate the attenuation of ischemic-reperfusion injury in the liver after sevoflurane preconditioning. In the presence of sevoflurane, an attenuation of liver injury is hypothesized (diminished increase of liver enzymes, reduced production of inflammatory mediators).
详细描述
Organ protection; preconditioning; volatile anesthetics; ischemia reperfusion
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Older than 18 years of age
- •Patients undergoing liver resection (benign or malignant tumors)
排除标准
- •Laparoscopic liver resection coagulopathy (platelets < 50,000/ml, Quick < 50%)
- •Liver cirrhosis
结局指标
主要结局
Blood levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT)
次要结局
未报告次要终点
研究者
研究点 (1)
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