NCT00518908已完成不适用
Role of Volatile Anesthetics for Hepatic Protection in Ischemia-reperfusion: Postconditioning
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 125
- 试验地点
- 1
- 主要终点
- Liver transaminase AST
研究概览
简要总结
Organ protection, volatile anesthetics, postconditioning, hepatic surgery
详细描述
This study aims at the evaluation of a potential attenuation of ischemic-reperfusion injury in the liver with sevoflurane postconditioning upon reperfusion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Sevoflurane
Experimental
Sevoflurane for pharmacological postconditioning
干预措施: Sevoflurane (Drug)
Propofol
Experimental
Anesthesia maintenance with propofol instead of Sevoflurane postconditioning
干预措施: Sevoflurane (Drug)
结局指标
主要结局
Liver transaminase AST
时间窗: Postoperative phase until discharge
Peak value
次要结局
- ALT peak value(Postoperative phase until discharge)
- Course of transaminases(From the day before surgery, to 6 hours after surgery, up to postoperative day 7)
- Need for prolonged intensive care unit stay (>24 hours)(Postoperative phase until discharge)
- Postoperative complications(Postoperative phase until discharge)
- Length of hospital stay(Postoperative phase until discharge)
研究者
研究点 (1)
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