Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation During Gastrointestinal Endoscopy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- intraoperative and postoperative monitoring of sedation during upper or lower gastrointestinal system endoscopy.
研究概览
简要总结
This study aims to compare efficacy of sedation between Dexmedetomidine-Propofol and Ketamine-Propofol combinations in the upper or lower gastrointestinal system endoscopy. We compare between 2 combinations as regard hemodynamic stability, post operative side effects as occurrence of delirium, nausea, vomiting, headache, hallucination or agitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists physical status I to II.
- •Age between 18 and 60 years.
- •Both sexes.
排除标准
- •Having severe heart, lung, liver disease, kidney failure, or bleeding disorder.
- •Patients having fever, hypothermia or infection, electrolyte disorders, such as hypokalemia and hypocalcaemia, acid-base disorder, allergy to drugs to be used.
研究组 & 干预措施
Dexmedetomidine-Propofol for sedation during gastrointestinal endoscopy
efficacy of sedation with Dexmedetomidine-Propofol combination in the upper or lower gastrointestinal system endoscopy.
干预措施: Dexmedetomidine-Propofol (Drug)
Ketamine-Propofol for sedation during gastrointestinal endoscopy
efficacy of sedation with Ketamine-Propofol combination in the upper or lower gastrointestinal system endoscopy.
干预措施: Ketamine-Propofol (Drug)
结局指标
主要结局
intraoperative and postoperative monitoring of sedation during upper or lower gastrointestinal system endoscopy.
时间窗: every 5 minutes intraoperative and every 15 minutes for 2 hours postoperative.
Sedation level
次要结局
未报告次要终点
研究者
Ahmed Hany Hamed
Resident, Department of Anesthesia, Intensive Care and Pain management, Faculty of Medicine, Sohag University
Sohag University