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临床试验/NCT03262597
NCT03262597已完成不适用

Beverage Hydration Index of Three Commercial Oral Rehydration Therapy ORT Beverages

Sonoma State University2 个研究点 分布在 1 个国家目标入组 46 人开始时间: 2017年2月17日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
46
试验地点
2
主要终点
Beverage hydration index

研究概览

简要总结

The "beverage hydration index" (BHI) assesses the hydration potential of any consumable fluid relative to water. The BHI is a relatively new metric. Our purpose was to assess the BHI of beverages never previously tested, including an amino acid-based oral rehydration solution (AA-ORS), a glucose-containing ORS (G-ORS) and a sports drink (SD) compared to water (control).

详细描述

The "Beverage Hydration Index" (BHI) was created to assess the degree to which beverages "hydrate", by measuring fluid retention after ingesting a 1 liter bolus and comparing it to water. Drinks with carbohydrates and electrolytes would traditionally be expected to score higher on the BHI due to glucose-sodium cotransport at the gut and osmolality approaching isotonicity with blood. One recent study reported that an oral rehydration solution (ORS) scored better than water, but a "sports drink" did not. No "optimal" BHI beverage composition has been described, nor has an optimal osmolality. Recently, a hypotonic amino acid-based rehydration beverage was developed to take advantage of amino acid-sodium cotransport, thus obviating the need for carbohydrate. However, the BHI of this beverage has not yet been assessed. The purpose of this investigation was to assess the hydration potential of this novel beverage in comparison to a commercially available carbohydrate-containing sports drink and oral rehydration solution.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy male or female
  • Aged 18-35
  • BMI 18-27 kg/m2
  • No known cardiovascular, renal or metabolic disease
  • Moderately active
  • Moderate alcohol use

排除标准

  • Overweight or obese (BMI >27 kg/m2)
  • Competitive athletes during competition season
  • Current or former cardiovascular, renal or metabolic disease
  • Habitual consumption of alcohol (>21 units/week) or regular (>1/week) high (10 units) intake*
  • History of psychiatric illness
  • Actively seeking to gain or lose weight
  • Currently taking prescribed medication
  • Example, a 750 ml bottle of wine at 12% ABV contains 0.750 Liters * 12 = 9 units

研究组 & 干预措施

Beverage Hydration Index of beverages

Experimental

Subjects will consume 4 different beverages to obtain the beverage hydration index.

干预措施: enterade (Other)

Beverage Hydration Index of beverages

Experimental

Subjects will consume 4 different beverages to obtain the beverage hydration index.

干预措施: Pedialyte (Other)

Beverage Hydration Index of beverages

Experimental

Subjects will consume 4 different beverages to obtain the beverage hydration index.

干预措施: Gatorade (Other)

Beverage Hydration Index of beverages

Experimental

Subjects will consume 4 different beverages to obtain the beverage hydration index.

干预措施: Water (Other)

结局指标

主要结局

Beverage hydration index

时间窗: 4 hours

beverage hydration index

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Kurt Sollanek

Assistant Professor

Sonoma State University

研究点 (2)

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