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临床试验/TCTR20230510003
TCTR20230510003已完成4 期

The effectiveness of intravenous dexamethasone prophylaxis before thyroidectomy in reducing postoperative pain, nausea and vomiting

Hua Hin Hospital0 个研究点目标入组 100 人开始时间: 2023年5月10日最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
100

研究概览

简要总结

In dexamethasone group, the mean pain score is significantly lower at recovery room admission and postoperative nausea and vomiting incidence is significantly lower at one hour after surgery compare to placebo group. No significantly differences in pain score and nausea and vomiting score at eight hours after surgery.

研究设计

研究类型
Interventional

入排标准

年龄范围
18 Years 至 65 Years(—)
性别
All

入选标准

  • 1. Patients age 18-65 years who underwent thyroid surgery, 2. ASA class 1 or 2, 3. Ideal Body Weight 40-80 kilogram

排除标准

  • 1. Patients with previous thyroid or neck surgery, 2. antiemetic consumption within 48 hours before surgery, 3. history of chronic pain, 4. history of DM or preoperative blood glucose more than 126 mg/dL, 5. history of postoperative nausea and vomiting, 6. pregnancy or lactation, 7. history of allergic reaction to medication used in this research, 8. history of underlying diseases that may be worsen by dexamethasone administration i.e. gastric ulcer

研究者

发起方
Hua Hin Hospital

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