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临床试验/NCT01896024
NCT01896024已完成不适用

Effects of Motive-Oriented Therapeutic Relationship in the Early-Phase Treatment of Borderline Personality Disorder

University of Lausanne Hospitals2 个研究点 分布在 1 个国家目标入组 85 人开始时间: 2010年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
85
试验地点
2
主要终点
Outcome Questionnaire -45.2 (Lambert et al., 2004)

研究概览

简要总结

The present research aims at examining the effectiveness of a specific set of therapist relational interventions and attitudes, called the Motive-Oriented Therapeutic Relationship (MOTR), based on Plan Analysis (Caspar, 2007) in the early-phase treatment of patients diagnosed with Borderline Personality Disorder.

The investigators intend to include N = 80 outpatients diagnosed with Borderline Personality Disorder, consulting at the Outpatient Personality Disorder Program of the Karl Jaspers Clinical Unit, in collaboration with the Institute of Psychotherapy, at the Department of Psychiatry-CHUV, University of Lausanne and in collaboration with the University of Berne, Switzerland. Patients are assigned by chance to two treatment conditions 1) Control condition (General Psychiatric Management; Gunderson & Links, 2008) and 2) MOTR-condition. The investigators hypothesize better results in the MOTR-condition, as compared to the control condition in terms of symptom reduction pre-post.

The conduct of the study represents a significant contribution to the understanding and enhancement of relationship aspects in the treatment of patients diagnosed with Borderline Personality Disorder which may be of potential benefit for these patients.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • DSM-IV Borderline Personality Disorder;
  • between 18 and 65 yrs of age

排除标准

  • DSM-IV psychotic disorders,
  • mental retardation,
  • substance abuse in the forefront

研究组 & 干预措施

General Psychiatric Management (GPM; Gunderson & Links, 2008)

Active Comparator

psychodynamic-psychiatric treatment for borderline personality disorder

干预措施: Psychiatric Management (Behavioral)

GPM plus Motive-Oriented Therapeutic Relationship

Experimental

use of Plan Analysis and Motive-oriented therapeutic relationship, as add-on variable to GPM

干预措施: Psychiatric Management (Behavioral)

GPM plus Motive-Oriented Therapeutic Relationship

Experimental

use of Plan Analysis and Motive-oriented therapeutic relationship, as add-on variable to GPM

干预措施: Motive-oriented therapeutic relationship/Plan Analysis (Behavioral)

结局指标

主要结局

Outcome Questionnaire -45.2 (Lambert et al., 2004)

时间窗: 3 months

pre- post- intervention in a randomized controlle trial; measure of symptom reduction over 3 months

次要结局

  • Inventory of Interpersonal Problems (Horowitz et al., 1988)(3 months)

研究者

发起方
University of Lausanne Hospitals
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ueli Kramer

PhD

University of Lausanne Hospitals

研究点 (2)

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