Long-term Management of Patients With Ruptured HCC
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 112
- 主要终点
- Survival after rupture of hepatocellular carcinoma
研究概览
简要总结
The main objective of this work is to evaluate the prevalence and results of specific management of HCC after spontaneous rupture, since the arrival of sorafenib in 2008.
详细描述
Retrospective, observational, multicenter study over the period from January 2008 to April 2024.
Cases had to be 18 years or older. They were identified by two different methodologies adapted to the 4 participating centers. In particular, a request for ICD10 C22.0 (CHC) codes associated with K66.1 (hemoperitoneum) was carried out by the medical information departments (DIM) of the Caen University Hospital and the Avicenne hospital. Secondly, the automated keyword selection tools "Cohort 360" and "i2b2" were used at the La Pitié Salpetrière and Paul Brousse hospital centers to identify the terms "CHC" and "ruptured" in the computerized patient files. Secondarily, duplicates and coding errors were excluded.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ruptured hepatocellular carcinoma with or without cirrhosis
排除标准
- •Liver adenoma without histologically proven HCC
- •Other benign or malignant liver tumors
- •ATCD of potentially triggering interventional procedure in the previous month.
- •Hemorrhagic ascites without tumor
- •Intratumoral hemorrhages without hemoperitoneum or capsular rupture
结局指标
主要结局
Survival after rupture of hepatocellular carcinoma
时间窗: 15 years
次要结局
未报告次要终点