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临床试验/NCT07034001
NCT07034001已完成不适用

Effect of Anesthesia on Frontal QRS-T Angle in Obese Individuals

Amasya University1 个研究点 分布在 1 个国家目标入组 93 人开始时间: 2024年12月1日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
93
试验地点
1
主要终点
Frontal qrs-t angle

研究概览

简要总结

The aim of this observational study is to determine the effect of anesthesia on frontal qrs-t angle changes in obese individuals. To learn the long-term effects of intervention A in individuals with a body mass index > 30 who received intervention A. The main question it aims to answer is:

Does frontal qrs-t angle change occur in obese individuals due to anesthesia? Preoperative and intraoperative ECG changes of individuals undergoing surgery will be examined.

详细描述

All patients were routinely administered 500 cc of Ringer's lactated solution intravenously (IV) before anesthesia and taken to the operating room. The body mass index will be calculated according to the formula body weight kg / height cm2. Obese patients with a BMI above 30 kg/m2 were recorded as group 2, and non-obese patients with a BMI below <30 kg/m2 were recorded as group 1. Patients were taken to the operating room and routine ECG, noninvasive blood pressure, pulse, and oxygen saturation monitoring (CARESCAPE™ B650, GE Healthcare, USA) was performed. All patients were hydrated intravenously (IV) with 500 cc of Ringer's lactated solution after a 6-hour fast. For premedication, midazolam 1 mg IV and pantoprazole 40 mg IV were administered. For anesthesia induction, propofol 2 mg/kg, fentanyl 2 mg/kg and rocuronium 0.6 mg/kg were administered intravenously.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • People between the ages of 18-65 who underwent laparoscopic cholecystectomy surgery

排除标准

  • known coronary artery disease, atrial fibrillation, heart failure, liver failure, kidney failure, preexcitation syndromes, electrolyte disorders, use of drugs that prolong the QT interval, respiratory failure and metabolic diseases were excluded from the study

结局指标

主要结局

Frontal qrs-t angle

时间窗: 1 day

Frontal qrs t angle examination on ecg

EKG

时间窗: 1 day

Frontal qrs t angle and qt interval examination on ecg

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Harun Tolga Duran

Ass. Prof.

Amasya University

研究点 (1)

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