The Effects of Two Different Ventilation Strategies on Lung Ventilation in Patients Undergoing Robotic Radical Prostatectomy: Ultrasonographic Evaluation.
试验速览
- 阶段
- 不适用
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- The difference between LUS Scores at T5 in patients ventilated with VCV and PCV
研究概览
简要总结
This study will be performed in robotic assisted laparoscopic radical prostatectomy patients in Cerrahpasa Medical Faculty Monoblock Operating Room. Since robot-assisted laparoscopic radical prostatectomy is a surgical procedure which requires long-term mechanical ventilation, excessive trendelenburg position (30-45 °) and pneumoperitoneum; these interventions may lead to respiratory complications such as ventilation difficulty and aeration loss in patients. Nowadays, lung ultrasonography has been used in anesthesia practice and intensive care units in order to determine lung aeration loss. In this study, the investigators aimed to compare the possible aeration loss in lung parenchyma during pressure controlled ventilation and volume controlled ventilation which are frequently used in anesthesia practice in patients undergoing robotic radical prostatectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Patient who will be undergo robot assisted laparoscopic prostatectomy surgery
- •Patient with ASA (American Society of Anesthesiologists) Score 1-3
排除标准
- •Patients with ASA Score above 3
- •Patients with obstructive (FEV1<%60) or restrictive pulmonary disease (FVC<%60)
- •Patients with intrathoracic operation history
- •Heavy smokers (>25 cigarettes/day)
研究组 & 干预措施
Pressure Controlled Ventilation
Patients undergoing pressure controlled ventilation
干预措施: Pressure Controlled Ventilation (Other)
Volume Controlled Ventilation
Patients undergoing volume controlled ventilation
干预措施: Volume Controlled Ventilation (Other)
结局指标
主要结局
The difference between LUS Scores at T5 in patients ventilated with VCV and PCV
时间窗: (T5) 60 minutes after patients come to the recovery room.
Lung Ultrasonography will be applied to patients after surgery in the recovery room at T5. Two different groups' LUS scores will be calculated and compared.
次要结局
- The difference between LUS Scores at T3 in patients ventilated with VCV and PCV((T3) 5 minutes after the surgical procedure is finished)
- The difference between LUS Scores at T2 in patients ventilated with VCV and PCV((T2) 5 minutes after intubation)
- The difference between LUS Scores at T4 in patients ventilated with VCV and PCV((T4) 5 minutes after taking the patient to supin position)
研究者
Hacer Zeynep Turgut
MD
Istanbul University