NCT04312256已完成不适用
Comparison of Flexor Hallicus Brevis and Adductor Pollicis as Sites for Neuromuscular Monitoring With Electromyography (Thumb vs Great Toe) After Sugammadex Administration
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 81
- 试验地点
- 2
- 主要终点
- Onset Time of Muscle Relaxation for Flexor Hallucis Brevis (Great Toe) and Adductor Pollicis (Thumb) Muscles
研究概览
简要总结
Researches are comparing the accuracy of measuring muscle relaxation in the thumb versus the great toe.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > or = 18 years old
- •Patients willing to participate and provide an informed consent
- •Patients undergoing an elective surgical procedure that requires use of non-depolarizing NMBA agents administered intraoperatively.
- •Patients with planned administration of sugammadex as a neuromuscular blocking reversal agent.
排除标准
- •Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
- •Patients with systemic neuromuscular diseases such as myasthenia gravis
- •Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment or end-stage liver disease.
- •Patients having surgery that would involve prepping the arm or leg into the sterile field
结局指标
主要结局
Onset Time of Muscle Relaxation for Flexor Hallucis Brevis (Great Toe) and Adductor Pollicis (Thumb) Muscles
时间窗: Up to 1 hour postoperatively
The amount of time before initial muscle relaxation is recorded via neurostimulation with the Tetragraph device. As measure in seconds.
Recover Time for Flexor Hallucis Brevis (Great Toe) and Adductor Pollicis (Thumb) Muscles
时间窗: Up to 1 hour postoperatively
The amount of time after muscle neurostimulation with the Tetragraph device completion to muscle full recovery. As measure in seconds.
次要结局
- Onset Time of Reversal Agent Administered for Flexor Hallucis Brevis (Great Toe) and Adductor Pollicis (Thumb) Muscles(Up to 1 hour postoperatively)
- Recover Time of Reversal Agent Administered for Flexor Hallucis Brevis (Great Toe) and Adductor Pollicis (Thumb) Muscles(Up to 1 hour postoperatively)
研究者
J. Ross Renew, M.D.
Principal Investigator
Mayo Clinic
研究点 (2)
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