Synovial Sarcoma Registry and Biospecimen Repository
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 2
- 主要终点
- Number of patients with synovial sarcoma
研究概览
简要总结
The purpose of this study is to collect and store data and samples for future research to attempt to improve outcomes for patients with synovial sarcoma. The future research will involve various types of genetic testing.
Participants will be asked to allow access to medical records and leftover tumor tissue and may be asked to give a blood or saliva sample. Participants will also be asked to completed questionnaires about their medical history and may be contacted every 6 to 12 months for updates for up to 10 years.
详细描述
This study will enroll patients with a diagnosis of Synovial Sarcoma.
Following consent, demographic, clinical, treatment and outcome data will be collected from an interview and/or online survey. This will include a request for contact information for the subject's treating hospitals/physicians and a release of records request to obtain medical records.
At approximately 6-12 month intervals for up to 10 years after initial diagnosis and/or relapse, subjects and/or their treating hospitals may be contacted to provide updates on treatment and outcomes.
Tumor samples may be collected from residual material obtained during clinically indicated procedures occurring before or after consent to this study. No additional material will be collected or procedures performed solely for the purpose of this study.
Blood may be collected at the participant's local institution at the time of a clinically indicated blood draw and/or saliva or a buccal swab may be collected as a germline sample and for analysis of circulating free DNA (cfDNA) and/or circulating tumor cells (CTCs).
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Males or females of any age
- •Reported diagnosis of synovial sarcoma
- •Informed consent from subject (aged ≥18 years) or parent/guardian
排除标准
- •Individuals with sarcomas that do not fit the definition of those considered for this registry
- •Individuals who are unwilling to participate
- •Individuals who are unwilling or unable to provide written consent
结局指标
主要结局
Number of patients with synovial sarcoma
时间窗: Up to 10 years
Number of patients with synovial sarcoma
次要结局
未报告次要终点