NCT00608998已完成不适用
Vascular Risk Factors and Coronary Calcifications in Chronic Renal Failure Patients: Identification of Specific Factors Linked to Renal Failure Progression
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- description of osteoprotegerin levels according to chronic renal failure progression
研究概览
简要总结
The aim of this study is to appreciate the influence of renal failure progression on vasculopathy (coronary calcifications and left ventricular hypertrophy) and cardiovascular risk factors.
详细描述
The aim of this study is to appreciate the relationship between:
- extension of coronary calcifications and chronic renal failure progression
- extension of coronary calcifications and levels of osteoprotegerin (bone disease marker)
- cardiovascular risk factors and coronary calcifications
- cardiovascular risk factors and existence of cardiovascular diseases
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient who has signed the written consent form
- •Patient aged > 18 and < 90 years
- •Chronic renal failure defined by glomerular filtration rate (GFR)
- •group 1: GFR >90 mL/min with urinary biological abnormalities and GFR comprised between 90 and 60 mL/min
- •group 2: GFR comprised between 60 and 30 mL/min
- •group 3: GFR <30 mL/min but without dialysis therapy
排除标准
- •Chronic renal failure patient requiring dialysis therapy
结局指标
主要结局
description of osteoprotegerin levels according to chronic renal failure progression
时间窗: inclusion
次要结局
- relationship between cardiovascular risk factors and cardiovascular disease(inclusion)
- osteoprotegerin description according to calcium score(inclusion)
- relationship between cardiovascular risk factors and calcium score(inclusion)
- calcium score description according to chronic renal failure progression(inclusion)
研究者
研究点 (1)
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