跳至主要内容
临床试验/CTRI/2025/06/089068
CTRI/2025/06/089068尚未招募不适用

Comparison of Analgesic Efficacy Between Ultrasound-Guided Paravertebral Block and Erector Spinae Plane Block Using Ropivacaine After Percutaneous Nephrolithotomy in Medical College Kolkata

Medical College Kolkata1 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2025年1月8日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
44
试验地点
1
主要终点
Comparison of Analgesic Efficacy Between Ultrasound-Guided Paravertebral Block and Erector Spinae Plane Block Using Ropivacaine After Percutaneous Nephrolithotomy in Medical College Kolkata

研究概览

简要总结

TITLE - COMPARISON OF ANALGESIC EFFICACY BETWEEN ULTRASOUND-GUIDEDPARAVERTEBRAL BLOCK AND ERECTOR SPINAEPLANE BLOCK USING ROPIVACAINE  AFTER PERCUTANEOUSNEPHROLITHOTOMY IN MEDICAL COLLEGE, KOLKATA

Acute postoperative pain after percutaneousnephrolithotomy surgery often hinders early recovery and may also lead tochronic post surgical pain, which lowers quality of life. Paravertebral blockis an excellent choice for postoperative analgesia. The erector spinae planeblock is also emerging as an effectivealternative.

Ropivacaine is a long-acting amide localanaesthetic. It exhibits a similar mechanism of action to other localanaesthetics in that it reversibly inhibits sodium ion influx in nerve fibers. Ropivacaine has some unique properties.Ropivacaine is less lipophilic than other local anaesthetics and is less likelyto penetrate large myelinated motor fibers. It, therefore, selectively acts onthe nociceptive

A, B, and Cfibers over the AB (motor) fibers resulting in a relatively reduced motorblockade. Thus, ropivacaine has a greater degree of motor sensorydifferentiation, which can be useful in this scenario where motor blockade isundesirable. Ropivacaine  hassignificantly less cardiotoxicity and neurotoxicity.  The aim of this study is tocompare the analgesic efficacy of paravertebral block anderector spinae plane block using Ropivacainein preventing acute post surgical pain following Percutaneous nephrolithotomy.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients posted for unilateral percutaneous nephrolithotomy under general anesthesia.
  • ASA Grade 1 and 2 patients.
  • Body weight between 50 kg to 70 kg.

排除标准

  • Patient refused to give consent.
  • Patient with contraindications for local anesthesia.
  • Patient with severe psychiatric disorders.
  • Renal stones which required more than one puncture, supra costal puncture.
  • Intraoperative excessive bleeding.
  • Obesity (BMI more than 30).Patient with history of chronic pain and drug abuse.

结局指标

主要结局

Comparison of Analgesic Efficacy Between Ultrasound-Guided Paravertebral Block and Erector Spinae Plane Block Using Ropivacaine After Percutaneous Nephrolithotomy in Medical College Kolkata

时间窗: 08 Months

次要结局

  • Hemodynamic Parameter & Side effects of any(June 2025 TO January 2026)

研究者

申办方类型
Government medical college

研究点 (1)

Loading locations...

相似试验