NCT00727753已完成不适用
Effects of Vascular Endothelial Growth Factor Antagonism With Ranibizumab or Bevacizumab in Patients With Neovascular Macular Degeneration
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- Change of endothelial function after 2 intravitreal injections and 8 weeks follow-up with ranibizumab or bevacizumab in patients with neovascular macular degeneration compared to patients with dry AMD.
研究概览
简要总结
The objective of this study is to evaluate the effects of 2 intravitreal injections with Ranibizumab or Avastin on endothelial function in subjects with neovascular macular degeneration compared to patients with dry AMD.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Ranibizumab
干预措施: Ranibizumab (Drug)
Bevacizumab
干预措施: Bevacizumab (Drug)
Dry AMD
干预措施: No treatment (Other)
结局指标
主要结局
Change of endothelial function after 2 intravitreal injections and 8 weeks follow-up with ranibizumab or bevacizumab in patients with neovascular macular degeneration compared to patients with dry AMD.
时间窗: 8 weeks
次要结局
- Change in cardiovascular and ophthalmological parameters.(8 weeks)
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Effect of Intravitreal Anti-VEGF on Retinal Vessels DiameterAge Related Macular DegenerationNCT01626339University of Malaya30
已完成
不适用
VEGF and PEDF in Patients With Myopic Choroidal NeovascularizationMyopic Choroidal NeovascularizationVEGF Aqueous LevelPEDF Aqueous LevelNCT02175940Università degli Studi di Brescia40
终止
不适用
Effect of Vascular Endothelial Growth Factor Blockers on Aqueous Humor DynamicsMacular DiseaseNCT01994174University of Nebraska13
Unknown
4 期
Ranibizumab for Myopic NeovascularizationMyopic Choroidal NeovascularizationNCT01246089Instituto de Olhos de Goiania20
已完成
2 期
PRP vs Bevacizumab for PDR TreatmentProliferative Diabetic RetinopathyNCT02705274Marashi Eye Clinic30