NCT05060770已完成不适用
Transcriptiomic Analysis of Inflammatory Bowel Disease-associated Colorectal Cancer. A French Retrospective Study of 26 Cases Identified at the Nancy University Hospital
Central Hospital, Nancy, France0 个研究点目标入组 26 人开始时间: 2010年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 26
- 主要终点
- IBD associated CRC oncogenesis
研究概览
简要总结
Chronic inflammatory bowel disease (IBD) is associated with an increased risk of colorectal cancer (CRC) in historical cohorts. The pathways of oncogenesis of these CRCs, which are very different clinically from de novo CRCs, are currently unknown. The aim of our work is to identify specific molecular signatures of CRC occurring in the setting of IBD.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Person 18 years of age or older
- •Person with colorectal cancer in the context of IBD
- •Person who has received complete information on the organization of the research and who has signed an informed consent
- •Person affiliated to a social security plan or beneficiary of such a plan.
排除标准
- •Person referred to in articles L. 1121-5, L. 1121-7 and L1121-8 of the public health code:
- •Pregnant woman, parturient or nursing mother
- •Minor (not emancipated)
- •Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
- •Person of legal age who is unable to express his or her consent
- •Person deprived of liberty by a judicial or administrative decision, persons subject to psychiatric care under articles L. 3212-1 and L. 3213-1.
结局指标
主要结局
IBD associated CRC oncogenesis
时间窗: 1 year
Percentage of gene expression variation in CRC tumor tissue samples in the following groups patients with CRC and IBD
次要结局
未报告次要终点
研究者
MULLER Marie
Doctor (MD, PhD Student), Principal investigator
Central Hospital, Nancy, France
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