Evolution of Alcohol Consumption Patterns After Bariatric Surgery and Associated Factors
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 350
- 试验地点
- 4
- 主要终点
- Alcohol consumption and alcohol use disorder
研究概览
简要总结
A large body of studies indicate an increase in alcohol use disorder (AUD) rates after bariatric surgery. However, little information exists on the evolution of other drinking patterns after surgery and the psychological predictors of problematic drinking postoperatively. The identification of these factors is necessary for the implementation of prevention strategies regarding postoperative problematic alcohol use. The aim of this research is to examine the evolution of various drinking patterns after bariatric surgery as well as the psychological factors associated with AUD and an increase in postoperative alcohol consumption.
详细描述
Obesity affects 15.9% of the Belgian population and remains a difficult disease to treat with traditional weight loss interventions. Its high prevalence and the negative consequences it entails make it a public health concern. Bariatric surgery is associated with long-term weight loss and an improvement in obesity-related comorbidities. However, despite its success in achieving significant and lasting weight loss, numerous studies raise the emergence of unpleasant psychosocial problems after the operation, including an increase of regular alcohol consumption and prevalence of AUD. Some of these studies are longitudinal and include large samples. For example, in a prospective multicenter study, King et al., (2017) found that more than 20% of patients with a bariatric surgery present symptoms of AUD within five years after surgery. Moreover, some studies suggest that, among patients with postoperative AUD, some had never suffered from alcohol problems before surgery.
Given the severe negative consequences of AUD for the individuals who suffer from it, their family and the society, better understanding the factors involved in postoperative alcohol use problems is necessary. However, little is known about predictors of post-bariatric surgery AUD. Known risk factors are: male gender, smoking, regular alcohol consumption before surgery, younger age, recreational drug use, lower sense of belonging and ADHD symptoms. Information is lacking about the psychological risk factors for postoperative AUD and regarding the evolution of problematic drinking patterns other than AUD after surgery.
Given the previously cited gaps in the scientific literature, the present research's aims are to study the evolution of different drinking patterns after bariatric surgery as well as the psychological factors associated with AUD and increased alcohol consumption postoperatively.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Being 18 years or older at the time of surgery
- •Having a body mass index (BMI) greater than or equal to 40 or a BMI greater than or equal to 35 with at least one obesity-related comorbidity
- •Having a scheduled surgery date
- •Fluency in French speaking
- •Being able to complete the questionnaires, i.e. have access to a computer or a smartphone
排除标准
- •Being a minor at the time of the operation
- •Having difficulty reading or understanding French.
- •Not having access to a computer or a smartphone to answer the questionnaires
结局指标
主要结局
Alcohol consumption and alcohol use disorder
时间窗: Before bariatric surgery and 6 months, one year, one and a half years and two years after surgery.
Alcohol consumption and presence of alcohol use disorder assessed using the Alcohol Use Disorders Identification Test (AUDIT). Scores on the AUDIT range from 0 to 40, with higher scores indicating more problematic alcohol use.
Binge drinking
时间窗: Before bariatric surgery and 6 months, one year, one and a half years and two years after surgery.
Frequency of binge drinking as evaluated by a three item questionnaire.
Alcohol Intoxication
时间窗: Before bariatric surgery and 6 months, one year, one and a half years and two years after surgery.
Frequency of alcohol intoxication assessed by a single item.
Drinking Motives
时间窗: Before bariatric surgery and 6 months, one year, one and a half years and two years after surgery.
Assessment of reasons for consuming alcohol using the Drinking Motives Questionnaire - Revised Short Form. This questionnaire is composed of 12 items and 4 subscales assessing four types of motivation to drink. Scores on each of the subscales range from 3 to 9, with higher scores indicating more motivations to drink.
Antecedents of alcohol use problems
时间窗: Before surgery only.
Assessment of the lifetime presence of alcohol problems using the CAGE questionnaire (CAGE as an acronym for "Cut down drinking", "Annoyed by criticism", "Guilty feelings" and "Eye-opener").This questionnaire is made up of 4 items to which participants can respond on a binary scale ("yes" or "no"). Two or more "yes" answers indicate an alcohol abuse problem.
Sensitivity to alcohol
时间窗: At 6 months and one year after surgery.
Single-question assessment of the extent to which participants perceive a change in their response to alcohol following bariatric surgery.
次要结局
- Experiential Avoidance(Before bariatric surgery and one and two years post-surgery.)
- Binge eating(Before bariatric surgery and one and two years post-surgery.)
- Emotional eating(Before bariatric surgery and one and two years post-surgery.)
- Grazing(Before bariatric surgery and one and two years post-surgery.)
- Emotion regulation(Before bariatric surgery and one and two years post-surgery.)
- Impulsivity(Before bariatric surgery and one year post-surgery.)
- Anxiety(Before bariatric surgery and 6 months, one year, one and a half years and two years after surgery.)
- Depression(Before bariatric surgery and 6 months, one year, one and a half years and two years after surgery.)
研究者
Esin ER
Principal Investigator
University of Liege