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临床试验/NCT07122934
NCT07122934已完成不适用

Posterior Circulation Clot Burden Score (Pc-CBS) Predicts Clinical Outcome After Acute Ischemic Stroke Related to Posterior Circulation Occlusions : An Externally Validated Radiological Score

Centre Hospitalier Universitaire Vaudois0 个研究点目标入组 1,828 人开始时间: 2003年2月1日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
1,828
主要终点
Modified rankin scale at three months

研究概览

简要总结

Posterior circulation strokes (PCS) represent ~30% of all ischemic strokes, but existing prognostic tools are limited, especially for non-basilar artery occlusions. Accurate early outcome prediction may aid treatment decisions and clinical trial design. We developed and externally validated the Posterior Circulation Clot Burden Score (PC-CBS), a radiological tool to predict 3-month functional outcome in acute ischemic stroke due to posterior circulation occlusion.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age >18 years old
  • admitted within 24h from last known well
  • symptomatic arterial occlusion. The following arterial occlusions were eligible for inclusion: the extracranial vertebral artery between the V0 and V3 segments; the intracranial portion of the vertebral artery; the basilar artery either in its proximal, mid and/or distal segment, the P1 and/or the P2 segments of the posterior cerebral artery.

排除标准

  • simultaneous clinical and/or radiological strokes in the posterior and anterior circulation

结局指标

主要结局

Modified rankin scale at three months

时间窗: 3 months

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. med. Alexander Salerno, MD-PhD

Senior registrar

Centre Hospitalier Universitaire Vaudois

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