跳至主要内容
临床试验/NCT01885416
NCT01885416已完成不适用

The Impact of Dairy Products on Postprandial Inflammation in Obese Males

Agroscope Liebefeld-Posieux Research Station ALP2 个研究点 分布在 1 个国家目标入组 21 人开始时间: 2013年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
21
试验地点
2
主要终点
Inflammation markers in blood plasma (IL-6, TNF-alpha)

研究概览

简要总结

The study will quantitatively evaluate the systemic, postprandial inflammatory and metabolic response to the ingestion of three different meals in obese subjects. The administered meals will differ in the proportion of dairy products. Postprandial response will be monitored during 6 hours after meal consumption.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
None

入排标准

年龄范围
25 Years 至 55 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • BMI ≥ 20 kg/m2
  • age 25-55 y
  • informed consent

排除标准

  • Physiological or psychological diseases
  • Allergies to food or intolerance to high-fat meal
  • Vegetarians
  • Chronic intake of drugs
  • Diabetes mellitus Type I and II
  • Debilitating kidney diseases
  • Debilitating liver diseases
  • Clinically established coronary heart diseases
  • Ingestion of vitamins or dietary supplements during the course of the study

结局指标

主要结局

Inflammation markers in blood plasma (IL-6, TNF-alpha)

时间窗: 0,6h

次要结局

  • Biomarkers in blood (serum insulin, plasma glucose, GLP-1, lipids)(0,1,2,4,6h)
  • Endotoxin in blood serum(0,6h)

研究者

发起方
Agroscope Liebefeld-Posieux Research Station ALP
申办方类型
Other
责任方
Principal Investigator
主要研究者

Guy Vergeres

Dr.

Agroscope Liebefeld-Posieux Research Station ALP

研究点 (2)

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