Dismantling Mindfulness: Contributions of Attention vs. Acceptance
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 104
- 试验地点
- 2
- 主要终点
- Change in Inventory of Depressive Symptomatology
研究概览
简要总结
This study addresses NCCAM's request for research that investigates the neuropsychological mechanisms underlying mind-body therapies, and for precise criteria and better delineation of meditation practices.
The purpose of this study is to assess the clinical efficacy and mechanism of action of 2 component practices of "mindfulness meditation", i.e. focused awareness (FA) and open monitoring (OM) in comparison to each other and to the standard package, Mindfulness-Based Cognitive Therapy (MBCT).
详细描述
Meditation, particularly mindfulness meditation, is one of the most popular Complementary and Alternative Medicine (CAM) therapies for alleviating emotional stress, depression and anxiety. While standardized meditation-based treatment packages like Mindfulness Based Stress Reduction (MBSR) and Mindfulness-based Cognitive Therapy (MBCT) have reliably shown sustained improvements in emotional disturbances and wellbeing, they contain so many different components and practices that the active ingredient cannot be ascertained. What is commonly called "Mindfulness" meditation is actually comprised of two separate practices: 1) focused awareness practice (FA), and 2) open-monitoring practice (OM). This project aims to create separate 8 week programs for FA and OM meditations, compare their clinical efficacy and investigate their separate mechanisms of action in individuals with clinically significant levels of persistent negative affect and depression. The clinical benefit and mechanism of action of focused awareness (FA) vs open-monitoring (OM) vs MBCT will be examined with a 3-armed randomized control trial of these 8 week interventions. Outcome variables include negative affect (depression, anxiety, stress) and wellbeing. Hypothesized mediating processes include objectively measured attention, emotion regulation and the basic wakefulness on which they depend.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •English-speaking
- •ages 18-65
- •mild-severe levels of depression or high level of negative affect
排除标准
- •age <18 or >65
- •inability to read and write in English
- •Extremely severe levels of depression
- •active suicidal ideation
- •presence of Axis I personality disorder
- •panic disorder
- •post-traumatic stress disorder
- •obsessive-compulsive disorder
- •eating disorder, or substance abuse/dependence
- •current psychotherapy
- •change in antidepressant medication type or dosage in the last 8 weeks.
- •Lifetime history exclusions:
- •bipolar disorder
- •psychotic disorders
- •persistent antisocial behavior or repeated self-harm,
- •borderline personality disorder,
- •organic brain damage
- •regular meditation practice
研究组 & 干预措施
Focused Attention (FA)
This 8 week program consists solely of focused attention practices, i.e. selected attention to an object (breath etc) and deselection of other stimuli
干预措施: Focused Attention (FA) (Behavioral)
Open-Monitoring (OM)
This 8-week program consists solely of open monitoring practices, or noticing and/or labeling the contents of ongoing experience ( thoughts, body sensations, emotions, seeing, hearing etc) without focusing on or deselecting any stimuli
干预措施: Open- Monitoring (Behavioral)
Mindfulness-Based Cognitive Therapy (MBCT)
The 8 week MBCT program follows the 2nd Edition (2012) manual (Segal, Williams, Teasdale) and includes both focused attention and open- monitoring practices
干预措施: Mindfulness-Based Cognitive Therapy (Behavioral)
结局指标
主要结局
Change in Inventory of Depressive Symptomatology
时间窗: baseline, 8 weeks, 20 weeks
30-item clinician administered interview about unipolar depression symptoms
change in Depression, Anxiety Stress Scale (DASS)
时间窗: baseline, week 2,4,6,8, 20
42-item self-report questionnaire on depression, anxiety and stress symptoms
change in Wellbeing Scale (WBS)
时间窗: baseline, 8 weeks, 20 weeks
73-item self-report questionnaire of psychological wellbeing
次要结局
- Sustained Attention to response Task (SART)(baseline, 8 weeks)
- Difficulties in Emotion Regulation Scale (DERS)(baseline, 8 weeks, 20 weeks)
- Attention Control Questionnaire (Derryberry & Reed, 2002)(baseline, 8 weeks, 20 weeks)
- Change in Facial EMG power from baseline to 8 weeks(baseline and 8 weeks)
- Change in alpha-theta EEG power from baseline to 8 weeks(baseline and 8 weeks)
研究者
Willoughby Britton
Assistant Professor of Psychiatry and Human Behavior
Brown University
