NCT05617573已完成不适用
Correlations Between Microscopic Features of Synovium and Clinical Parameters in Patients With Advanced Osteoarthritis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 272
- 试验地点
- 1
- 主要终点
- Correlation between pathological features and laboratory index
研究概览
简要总结
To study synovial membrane (SM) inflammation in suprapatellar fossa in advanced knee osteoarthritis (OA), and to correlate the pathological features with clinical findings.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 55 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing elective, unilateral, primary TKA for advanced osteoarthritis.
排除标准
- •revisions, bilateral procedures, alcohol or medical abuse, administration of any glucocorticoids during the 3 months prior to surgery, and/or a history of serious cardiac or cerebrovascular problems, severe liver or kidney failure, and/or connective tissue disease including rheumatoid arthritis, ankylosing spondylitis, and systemic lupus erythematosus.
结局指标
主要结局
Correlation between pathological features and laboratory index
时间窗: 1 day
Correlation between pathological features and clinical scores
时间窗: 1 day.
次要结局
未报告次要终点
研究者
Xiang Shuai, MD
Principal Investigator
The Affiliated Hospital of Qingdao University
研究点 (1)
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