Saphenous (Adductor Canal) Nerve Block Versus Femoral Nerve Block for Total Knee Arthroplasty: A Novel Approach for Postoperative Analgesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 94
- 试验地点
- 1
- 主要终点
- Quadriceps Muscle Strength
研究概览
简要总结
Currently, the regional anesthetic standard of care for total knee replacement surgery is combined spinal/epidural, with or without a femoral nerve block, or FNB. Lasting approximately 18 hours, the FNB works by numbing the femoral nerve (and its branches), which is the major nerve controlling the knee joint. The femoral nerve also provides movement and sensation. While this regional anesthetic technique offers significant postoperative pain relief, it is possible that it may cause muscle weakness and increase patients' recovery time. Hence there is a need for an alternative technique, one that may help minimize postoperative pain as effectively as the FNB, while not causing weakness of the quadriceps muscle.
The saphenous nerve, a branch of the femoral nerve, provides sensation to the knee. Thus it is hypothesized that by "blocking" or anesthetizing the saphenous nerve with local anesthetic closer to where it branches off, the area around and below the knee will feel numb. Yet unlike with the FNB, the quadriceps muscle itself will still be able to function.
Patients will be randomized to receive FNB or saphenous nerve block. Quadriceps strength will be tested using a dynamometer before surgery (baseline), 6-8 hours following anesthesia administration, and on postoperative days 1 and 2. It is hypothesized that patients who receive FNB will experience a 50% decrease in quadriceps strength compared to baseline.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients ages 18-90 undergoing primary unilateral total knee arthroplasty
- •Planned use of neuraxial anesthesia
- •Ability to follow study protocol
- •American Society of Anesthesiology (ASA) Class 1-3
排除标准
- •Contraindication to a spinal or epidural anesthetic
- •Chronic opioid use (defined as daily or almost daily use of opioids for >3 months)
- •Hypersensitivity and/or allergy to local anesthetics
- •Intraoperative use of any volatile anesthetic
- •Patients with a pre-existing neuropathy on the operative limb
- •Contraindication to a femoral nerve block or saphenous nerve block
- •Allergy to any of the study medications
- •Non-English speaking patients
结局指标
主要结局
Quadriceps Muscle Strength
时间窗: 48 hours following administration of anesthesia.
Measurements were made by a handheld dynamometer while patients perform isometric exercises. Results are presented in kilogram-force (kgF) units. One kgF is equal to 9.80665 N.
次要结局
- Total Length of Hospital Stay(Total length of hospital stay)
- NRS Pain Scores at Rest(Postoperative day 4.)
- Total Opioid Usage(Postoperative day 4.)
- Patient Satisfaction With the Nerve Block.(24 hours following administration of anesthesia.)
- Incidence of Postoperative Complications.(Postoperative day 4.)
