Cardio Pulmonary Exercise Testing (CPET) in Diseases and Health
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 2
- 主要终点
- Maximal Oxygen consumption
研究概览
简要总结
Cardiopulmonary exercise test (CPET) is a helpful tool for evaluation of aerobic exercise capacity and tolerance for variety of population. CPET provides a full assessment of the physiologic responses of the pulmonary, cardiovascular, muscular, and cellular oxidative systems to exercise. The test progression include a incremental stepwise (on treadmill) or ramp control protocol (on bike ergometer ) to exhaustion. Measurement of respiratory gas exchange i.e. oxygen uptake, carbon dioxide, minute ventilation, other variables while monitoring ECG, blood pressure, pulse oximetry and exertion perceived (Borg Scale) during an incremental test .
Aim: To compere exercise responses for maximal exercise testing with different population.
详细描述
Each participants will conducted an exercise test on treadmill using Modified Bruce Protocol) or cycle ergometer. Quark CPET metabolic cart (Cosmed, Rome, Italy) will be use to collect and analysis gas exchange. 10 minute after the graded exercise test Supra maximal exercise test (SMT) will be done for 2 minutes one stage (treadmill protocol) or 10% at cycle protocol higher than highest load achieved in the incremental test.
all outcome measurement will be collected. Exercise tolerance and responses will be assess using the data of : pulmonary gas exchange; cardiovascular performance, and skeletal muscle metabolism.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 4 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •*Patient who invited to the clinic to do incremental maximal exercise test or healthy *Participants with no known significant health problems.
排除标准
- •Acute fever
- •Acute myocardial infarction within 2 to 3 days.
- •Unstable angina not previously stabilized by medical therapy.
- •Uncontrolled cardiac arrhythmias causing symptoms or hemodynamic compromise.
- •Symptomatic severe aortic stenosis.
- •Uncontrolled symptomatic heart failure.
- •Inability to perform exercise Orthopedic impairment severely compromising exercise performance.
结局指标
主要结局
Maximal Oxygen consumption
时间窗: through study completion, an average of 1 year
the maximum amount of oxygen that an individual can utilize during intense or maximal exercise.
Maximal Blood pressure
时间窗: through study completion, an average of 1 year
the blood pressure in the end of intense or maximal exercise.
Maximal Heart rate
时间窗: through study completion, an average of 1 year
the maximum heart rate achieved during intense or maximal exercise.
次要结局
- Ventilation Anaerobic Threshold(through study completion, an average of 1 year)
研究者
Gur Mainzer
Head of the pediatric cardiology department
The Baruch Padeh Medical Center, Poriya