comparison of dexmeditomidine as an adjunct to 0.1%ropivacaine to plain ropivacaine in adductor canal block for unilateral total knee replacement:a prospective,double blinded randomized controlled study

The main aim of this study is to investigate the duration of analgesia of ACB using ropivacaine with and without dexmedetomidine after unilateral TKR in first 24 hrs, both at rest and moving and to record pain score and opioid consumption among 2 groups.The study population will be composed of patients of either gender,aged above 18 years and below 80 years and posted for unilateral total knee replacement under spinal anesthesia at a tertiary health care centre.Data will be collected between Jan 2023 to july 2024.Analysis of the parameters will be done after complete data collection.At any point of time,the patients  enrolled can be dropped out of the study.

Sample size is calculated as 64 in number,which will be div ided into 2 groups, control group(C) and Dexmedetomidine  group (D).Control group consisting of 0.1% Ropivacaine 20mL and Dexmedetomidine group with 0.1% Ropivacaine  + 0.5mcg/kg Demedetomoidine through adductor canal block and Pain assessment done postoperatively evry 6th hourly for 24 hours and results assessed including the Pain score, side effects of adjuvant dexmedetomidine and opiod consumption.