Clinical Outcomes of Topical Ganciclovir Treatment in Cytomegalovirus Anterior Uveitis
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Anterior chamber inflammation
研究概览
简要总结
The purpose of this study was to evaluate long term efficacy and safety of topical ganciclovir treatment in Cytomegalovirus (CMV) anterior uveitis.
详细描述
The investigators will enroll 60 patients with positive results of the CMV PCR (polymerase chain reaction) from aqueous humor tapping from January 2006 to June 2011. All the patients (40 men, 20 women) were immunocompetent and diagnosed as symptomatic CMV infection. Their medical records will be reviewed, including demographic data as well as their ophthalmic and medical histories.
The purpose of this study was to evaluate long term efficacy and safety of topical ganciclovir treatment in CMV anterior uveitis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with positive results of the CMV PCR (polymerase chain reaction) from aqueous humor tapping. All the patients were immunocompetent and diagnosed as symptomatic CMV infection.
排除标准
- •Patients without positive results of the CMV PCR
- •Immunocompromised patients with positive results of the CMV PCR
结局指标
主要结局
Anterior chamber inflammation
时间窗: 4 weeks after starting treatment
anterior chamber cell grading based on slit lamp microscopy
次要结局
- probability of relapse-free(2 years after treatment)