Comparing Activity of Accessory Inspiratory Muscles and Upper Limb Muscles During Performing Activities of Daily Living Between Patients With Chronic Obstructive Pulmonary Disease and Healthy Adults
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Modified Medical Research Council
研究概览
简要总结
The purpose of this study attempts to investigate the differences and relationships of respiratory parameters, muscle activity, and dyspnea during ADL between patients with COPD and age-matched healthy participants.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •40 years or older
- •With the clinical diagnosis of COPD
排除标准
- •With the clinical diagnosis of asthma or cancer
- •With cardiovascular, musculoskeletal and neurological diseases limiting physical activities in daily life
- •In the unstable medical state
- •MMSE under 25
- •Barthel index score under 61
结局指标
主要结局
Modified Medical Research Council
时间窗: baseline
This is a five-point scale to assess the severity of breathlessness.
Modified Borg Scale
时间窗: baseline
This is a self-reported scale to measure how much participants perceive dyspnea. The range from 0 which means no difficulty to breathe to 10 which means with maximal difficulty to breathe.
Cardiopulmonary exercise testing device
时间窗: baseline
The machine analyze the breath of participants including oxygen consumption and minute ventilation volume. Oxygen consumption is reported in mL/min and minute ventilation volume is reported in L/min.
Surface electromyography device
时间窗: baseline
The surface EMG is performed to assess the maximum voluntary contraction and muscle activity of upper limb muscles and accessory inspiratory muscles during performing simulated ADL tasks. The maximal voluntary contraction (MVC) is used as the reference level of muscle activity to normalize the EMG data of performing simulated ADL tasks. The muscle activity is reported in percentage.
The clinical Chronic Obstructive Pulmonary Disease questionnaire
时间窗: baseline
This is a self-reported questionnaire to measure the impact of COPD on participants' health status. The rating scores is a 7-point scale (0=no limitation, 6=totally limited).Higher scores mean the more severe impact of COPD on participants' daily living.
次要结局
- EQ-5D questionnaire(baseline)