跳至主要内容
临床试验/NCT04654598
NCT04654598已完成不适用

Could the Consumption of Water From Plastic Bottles Affect the Embryo Grade and Clinical Pregnancy Rate Obtained With IVF/ICSI in Low Ovarian Reserve

Nefise Nazlı YENIGUL1 个研究点 分布在 1 个国家目标入组 74 人开始时间: 2019年4月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
74
试验地点
1
主要终点
Exposure to BPA

研究概览

简要总结

The relationship between BPA elevation in urine, blood, and follicle fluid and embryo quality, IVF/ICSI outcomes.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
25 Years 至 45 Years(Adult)
性别
Female
接受健康志愿者
是

入选标准

  • •patients who underwent IVF due to low ovarian reserve
  • •patients provided urine, blood, and follicle fluid (FF) samples on the oocyte retrieval day
  • •patients who did not smoke or use alcohol
  • •patients did not work in the plastic industry

排除标准

  • •patients who underwent IVF due to unexplained infertility or tubal factor or male factor indications
  • •patients diagnosed with endometriosis
  • •patients with freeze-all cycles
  • •patients having previous ovarian surgery
  • •women with metabolic disease (such as hypertension or diabetes mellitus)
  • •patients with a known genetic problem (male or female)

研究组 & 干预措施

BPA level

Other

BPA (bisphenol A) in urine, blood and follicle fluid samples

干预措施: BPA levels (Other)

结局指标

主要结局

Exposure to BPA

时间窗: 6 month

Concentrations of Bisphenol A (BPA) will be quantified in the urine, blood plasma, and follicular fluid (individual and pooled samples) by use of ELİSA test in women with low ovarian reserve

次要结局

未报告次要终点

研究者

发起方
Nefise Nazlı YENIGUL
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Nefise Nazlı YENIGUL

Ph.D. Assistant Professor, Principal Investigator

Sanliurfa Mehmet Akif Inan Education and Research Hospital

研究点 (1)

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