NCT02966444Unknown不适用
Hunger, Satiety, and Metabolic Responses to High-fat Meals of Varying Fatty Acid Composition
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- Peptide-YY
研究概览
简要总结
This study evaluates the effects of dietary fatty acid composition from high fat meals on markers of hunger, satiety and metabolism.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •BMI of >18.5-24.9kg/m2
- •18-40yrs of age
排除标准
- •Evidence of weight loss or gain exceeding 5% of their body weight within the past 3 months.
- •Plans to lose weight or begin a weight loss program between initiation of study and final testing.
- •Plans to begin an exercise program or change current exercise routines between initiation of study and final testing.
- •Is on a medically prescribed diet
- •Does not consume breakfast regularly
- •Rate less than 80% of foods offered in the buffet at 50mm or more on the 100mm VAS as palatable
- •Medications that could influence appetite or sensory function
- •Reports of metabolic or endocrine disease, gastrointestinal disorders, or history of medical or surgical events that could affect fat digestion and hormone signaling.
- •Any chronic disease including type II diabetes, hypothyroidism, hyperthyroidism, cardiovascular disease, and cancer
- •Any supplements that a subject begins taking between initiation of study and final testing.
- •Anyone who is currently pregnant, lactating, or planning on becoming pregnant before the conclusion of this study.
- •Anyone who has allergies to any of the components of the liquid meals
- •Anyone who has donated blood in the last 20 days
研究组 & 干预措施
PUFA-rich HF Meal
Experimental
High-fat meal rich in polyunsaturated fatty acids
干预措施: PUFA-rich HF Meal (Other)
SFA-rich HF Meal
Experimental
High-fat meal rich in saturated fatty acids
干预措施: SFA-rich HF Meal (Other)
MUFA-rich HF Meal
Experimental
High-fat meal rich in monounsaturated fatty acids
干预措施: MUFA-rich HF Meal (Other)
结局指标
主要结局
Peptide-YY
时间窗: 18 months
次要结局
- Visual Analog Scale(18 months)
研究者
Jada Stevenson
Assistant Professor
Texas Christian University
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Differential effects of saturated & unsaturated fats on satiety and energy intakeOverweight/obesityDiet and Nutrition - ObesityACTRN12610000193077actopharma18
已完成
不适用
To compare the effect of meals rich in saturated fat, canola oil and bran on postprandial levels of pro-inflammatory cytokines and interleukin-8 in obese and non-obese subjectsACTRN12606000337572ational Heart Foundation of New Zealand18
已完成
1 期
Study to Assess the Effect of Food on a Single Dose of Acoramidis in Healthy Adult ParticipantsHealthyNCT04958135Alexion Pharmaceuticals, Inc.18
已完成
不适用
Acute Effects of Fats on Satiety and Energy NeedsObesityNCT02496936USDA Grand Forks Human Nutrition Research Center23
终止
不适用
Chronic Effects of Fats on Satiety & Energy NeedsOverweightObesityNCT03236181USDA Grand Forks Human Nutrition Research Center1