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临床试验/NCT02496936
NCT02496936已完成不适用

Acute Effects of Fats on Satiety and Energy Needs

USDA Grand Forks Human Nutrition Research Center2 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2015年12月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
23
试验地点
2
主要终点
Acute effect of fat intake on energy expenditure as determined by metabolic rate

研究概览

简要总结

The purpose of this study is to assess the acute effect of dietary fat on satiety and energy metabolism.

详细描述

The influences of specific dietary fat sources on satiety, appetite and energy utilization remains unclear; evidence is lacking on whether responses vary according to acute intake. The researchers will use a controlled setting to determine whether the source of dietary fat is related to perceived satiety, satiety hormone responses, and energy expenditure by conducting experiments to evaluate short term (acute) effects.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • body mass index between 18.0-34.9 kg/m2
  • free of major diagnosed, untreated medical conditions
  • controlled hypertension
  • non-smoking or use of other tobacco products, including e-cigarettes
  • not taking steroid-based medications
  • not planning to or currently attempting to gain or lose weight
  • willing to comply with study demands
  • use of oral contraceptives
  • low intake of long chain omega 3 fatty acids

排除标准

  • diagnosed eating disorders
  • diabetes (blood sugar ≥ 126 mg/dl)
  • hypertension (systolic ≥ 160 mmHg or diastolic > 100 mmHg)
  • diagnosed cardiovascular, pulmonary, skeletal and metabolic disease
  • currently pregnant or planning to become pregnant, or lactating
  • taking medications known to affect appetite, blood lipids, body composition, body weight, or food intake (appetite control drugs, steroids, antidepressants)

结局指标

主要结局

Acute effect of fat intake on energy expenditure as determined by metabolic rate

时间窗: Incremental Area Under the Curve (iAUC) of metabolic rate from 0 to 4 hours

次要结局

未报告次要终点

研究者

发起方
USDA Grand Forks Human Nutrition Research Center
申办方类型
Fed
责任方
Sponsor

研究点 (2)

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