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Clinical Trials/NCT02496936
NCT02496936
Completed
Not Applicable

Acute Effects of Fats on Satiety and Energy Needs

USDA Grand Forks Human Nutrition Research Center1 site in 1 country23 target enrollmentDecember 2015
ConditionsObesity

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obesity
Sponsor
USDA Grand Forks Human Nutrition Research Center
Enrollment
23
Locations
1
Primary Endpoint
Acute effect of fat intake on energy expenditure as determined by metabolic rate
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The purpose of this study is to assess the acute effect of dietary fat on satiety and energy metabolism.

Detailed Description

The influences of specific dietary fat sources on satiety, appetite and energy utilization remains unclear; evidence is lacking on whether responses vary according to acute intake. The researchers will use a controlled setting to determine whether the source of dietary fat is related to perceived satiety, satiety hormone responses, and energy expenditure by conducting experiments to evaluate short term (acute) effects.

Registry
clinicaltrials.gov
Start Date
December 2015
End Date
October 30, 2019
Last Updated
3 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
USDA Grand Forks Human Nutrition Research Center
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • body mass index between 18.0-34.9 kg/m2
  • free of major diagnosed, untreated medical conditions
  • controlled hypertension
  • non-smoking or use of other tobacco products, including e-cigarettes
  • not taking steroid-based medications
  • not planning to or currently attempting to gain or lose weight
  • willing to comply with study demands
  • use of oral contraceptives
  • low intake of long chain omega 3 fatty acids

Exclusion Criteria

  • diagnosed eating disorders
  • diabetes (blood sugar ≥ 126 mg/dl)
  • hypertension (systolic ≥ 160 mmHg or diastolic \> 100 mmHg)
  • diagnosed cardiovascular, pulmonary, skeletal and metabolic disease
  • currently pregnant or planning to become pregnant, or lactating
  • taking medications known to affect appetite, blood lipids, body composition, body weight, or food intake (appetite control drugs, steroids, antidepressants)

Outcomes

Primary Outcomes

Acute effect of fat intake on energy expenditure as determined by metabolic rate

Time Frame: Incremental Area Under the Curve (iAUC) of metabolic rate from 0 to 4 hours

Study Sites (1)

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