Acute Effects of Fats on Satiety and Energy Needs
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obesity
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
- Enrollment
- 23
- Locations
- 1
- Primary Endpoint
- Acute effect of fat intake on energy expenditure as determined by metabolic rate
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The purpose of this study is to assess the acute effect of dietary fat on satiety and energy metabolism.
Detailed Description
The influences of specific dietary fat sources on satiety, appetite and energy utilization remains unclear; evidence is lacking on whether responses vary according to acute intake. The researchers will use a controlled setting to determine whether the source of dietary fat is related to perceived satiety, satiety hormone responses, and energy expenditure by conducting experiments to evaluate short term (acute) effects.
Investigators
Eligibility Criteria
Inclusion Criteria
- •body mass index between 18.0-34.9 kg/m2
- •free of major diagnosed, untreated medical conditions
- •controlled hypertension
- •non-smoking or use of other tobacco products, including e-cigarettes
- •not taking steroid-based medications
- •not planning to or currently attempting to gain or lose weight
- •willing to comply with study demands
- •use of oral contraceptives
- •low intake of long chain omega 3 fatty acids
Exclusion Criteria
- •diagnosed eating disorders
- •diabetes (blood sugar ≥ 126 mg/dl)
- •hypertension (systolic ≥ 160 mmHg or diastolic \> 100 mmHg)
- •diagnosed cardiovascular, pulmonary, skeletal and metabolic disease
- •currently pregnant or planning to become pregnant, or lactating
- •taking medications known to affect appetite, blood lipids, body composition, body weight, or food intake (appetite control drugs, steroids, antidepressants)
Outcomes
Primary Outcomes
Acute effect of fat intake on energy expenditure as determined by metabolic rate
Time Frame: Incremental Area Under the Curve (iAUC) of metabolic rate from 0 to 4 hours