NCT02676518Unknown不适用
Anti-Müllerian Hormone and Its Association With Glucose Intolerance and Metabolic Syndrome in Women With Polycystic Ovary Syndrome
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Differences between serum AMH level between PCOS women with and without glucose intolerance and metabolic syndrome
研究概览
简要总结
Association between serum anti-Mullerian hormone (AMH) level and prevalence of glucose intolerance and metabolic syndrome in women with polycystic ovary syndrome (PCOS)
详细描述
- To study the association between serum anti-Mullerian hormone (AMH) level and glucose intolerance and metabolic syndrome in women with polycystic ovary syndrome (PCOS).
- Glucose intolerance is detected by 2-hours 75 gram oral glucose tolerance test (OGTT).
- Metabolic syndrome is diagnosed by using the Harmonized criteria; the presence of any 3 of 5 following risk factors constitutes a diagnosis of metabolic syndrome.
- Elevated waist circumference (> 80 cm in Asian women)
- Elevated triglycerides (> 150 mg/dL)
- Reduced HDL-cholesterol (< 50 mg/dL)
- Elevated blood pressure )systolic > 130 and/or diastolic > 85 mmHg)
- Elevated fasting glucose ( > 100 mg/dL)
- Percentage of glucose intolerance and metabolic syndrome in PCOS women as well was any differences in parameters between PCOS patients with and without glucose intolerance and metabolic syndrome will be analysed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •PCOS diagnosed by Rotterdam criteria 2003
排除标准
- •Pregnancy
- •Previous any hormonal uses in the last 3 months
- •Previous hypoglycemic drugs or insulin-sensitising agents use in the last 3 months
- •Previous chemotherapy, ovarian surgery, pelvic irradiation
- •Menopause
结局指标
主要结局
Differences between serum AMH level between PCOS women with and without glucose intolerance and metabolic syndrome
时间窗: 6 months
Any differences between mean of serum AMH levels in PCOS with and without glucose intolerance and metabolic syndrome
次要结局
- Percentage of metabolic syndrome in PCOS women(6 months)
- Percentage of glucose intolerance in PCOS women(6 months)
研究者
Porntip Sirayapiwat
Principal Investigator
Chulalongkorn University
研究点 (1)
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