Effect of Endometrial Thickness on IVF Outcome: a Prospective Observational Study of Both Cleavage Stage and Blastocyst Stage Embryo Transfer Cycles
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Ongoing pregnancy rate
研究概览
简要总结
Although many studies have evaluated the relationship between endometrial thickness and IVF outcome, the results are still controversial. We notice that, during our daily work, for patients undergoing cleavage stage embryo transfer, endometrial thickness seems to have a huge impact on IVF outcome; however, for blastocyst stage embryo transfers, IVF outcome seems to have little association with endometrial thickness. Thus, the aim of this prospective observational study is to explore the relationship between endometrial thickness and IVF outcome in patients undergoing cleavage stage and blastocyst stage embryo transfers, respectively.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 22 Years 至 38 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •age between 22-38 years old;
- •the first cycle of IVF treatment with standard long protocol;
- •transfrred with at least two high quality cleavage stage embryos, or with at least one high quality blastocyst stage embryo.
排除标准
- •PGD cycles;
- •gamete donation cycles
结局指标
主要结局
Ongoing pregnancy rate
时间窗: 12 weeks after embryo transfer
An ongoing pregnancy was defined as a pregnancy with a positive heartbeat by ultrasound after 12 weeks gestation.
次要结局
未报告次要终点
研究者
Yingpu Sun
Director of Reproductive Medical Center
The First Affiliated Hospital of Zhengzhou University