NCT07700394已完成不适用
A Comparison Between Different Treatment Options For Mature Teeth With Apical Periodontitis: A Randomized Control Trial
Sara Tariq Elemam1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2021年12月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Healing in terms of volumetric change of lesion anlayized by CBCT
研究概览
简要总结
A randomized control trial which aim to compare the healing potential for the following treatment options for mature teeth with apical periodontitis:
Group I: Conventional root canal treatment (CRT) Group II: Regenerative endodontic treatment (RET) using a blood clot scaffold Group III: RET using a blood clot scaffold loaded with recombinant human BMPs (rhBMPs)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients aged 18-30 years
- •Healthy patients with no systemic diseases or known allergic reactions
- •Mature permanent molars diagnosed with pulp necrosis
- •Presence of a medium sized periapical lesion confirmed clinically and radiographically (PAI=3,4,5)
排除标准
- •Patients with generalized chronic periodontitis
- •Presence of small periapical lesions (PAI=1,2)
- •Periodontal pockets > 3 mm
- •Presence of systemic diseases or known hypersensitivity to any material used in the study
研究组 & 干预措施
Regenerative endodontic treatment
Experimental
干预措施: Regeneration (Procedure)
Conventional RCT
Active Comparator
干预措施: root canal treatment and intracanal medicament (Procedure)
RET using a BMPs
Experimental
干预措施: Regeneration with BMPs (Procedure)
结局指标
主要结局
Healing in terms of volumetric change of lesion anlayized by CBCT
时间窗: 1 year
Healing in terms of volumetric change of lesion analyzed by CBCT
时间窗: 1 year
次要结局
未报告次要终点
研究者
Sara Tariq Elemam
Doctor
Ain Shams University
研究点 (1)
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