The Effect of Time Restricted Feeding on Fat Mass in Overweight Women
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- Fat mass change over 4 weeks period of intervention
研究概览
简要总结
Participants will complete a one-month intervention where they are will restrict their daily food intake to an 8-hour time period, i.e., between 1200 to 2000 hours. During the remaining 16-hour intermittent fasting period (2000 to 1200 hours) participants will be allowed to drink zero calorie beverages (diet soda pop, black coffee, tea, water, etc) in order to maintain normal hydration. There will be no attempt to restrict food intake. Rather simply to restrict the time period each day when food is consumed. Participants' body mass, fat mass, and non-fat mass will be monitored non-invasively using a weigh scale and densitometry via air displacement (Bod Pod) at 0, 2 and 4 weeks following the dietary intervention. Also, participants will be interviewed following the final body composition measure to assess whether or not they continued to follow the intermittent fasting approach.
详细描述
Participants (16 overweight women, BMI (Body mass index) ˃25, ages 18- 30 y)will complete a one-month intervention where they will restrict their daily food intake to an 8-hour time period, i.e., between 1200 to 2000 hours. During the remaining 16-hour intermittent fasting period (2000 to 1200 hours) participants will be allowed to drink zero calorie beverages (diet soda pop, black coffee, tea, water, etc) in order to maintain normal hydration. There will be no attempt to restrict food intake. Rather simply to restrict the time period each day when food is consumed. Participants' fat mass will be monitored non-invasively using densitometry (with a Bod Pod) prior to and following a 4 week intervention where the participants will eat their normal daily intake during an 8-hour period each day (1200 to 2000 hours). The Bod Pod measures body volume via air displacement and together with an accurate measure of body mass enables body density to be calculated (Density = mass/volume). Satisfaction, hunger, and fullness with the diet will be monitored on a weekly basis using a validated visual analog scale (Flit et al, 2000). Adherence to the diet will also be assessed on a weekly basis as the number of days the diet was followed. During the 16-hour fasting period participants will be able to drink as much of zero calorie beverages as they desire. On day 2, 7, 14, 21, & 28 participants will return to the lab at 8am (following a 12 hour fasting period) and both the acidity of their urine (using a urine dip stick) and their blood sugar (using a glucometer) will be tested. Following one month the participants will be allowed either to continue this eating pattern or revert to their prior 3 meal intake. After a month of self-regulation, the participants' fat mass will be measured again using the Bod Pod.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Asymptomatic participants between the ages of 18-30 years with body mass index ˃25 will be studied
排除标准
- •Individuals with a history of fainting
- •Low blood sugar
- •Heart disease, migranes, or heart burn
- •Participants less then 18 of age
- •Anyone who for health or performance reasons should not skip breakfast will be excluded. These will be assessed by self report
结局指标
主要结局
Fat mass change over 4 weeks period of intervention
时间窗: 4 weeks
Body fat mass change (%) will be measured using BodPod over the course of 4 weeks at 0, 2 and 4 weeks
次要结局
- Non-fat mass change over 4 weeks period of intervention(4 weeks)
- Urine acidity change over 4 weeks of intervention(4 weeks)
- Feeling of fullness change over 4 weeks of intervention(4 weeks)
- Diet satisfaction change over 4 weeks of intervention(4 weeks)
- Blood sugar change over 4 weeks of intervention(4 weeks)
- Feeling of hunger change over 4 weeks of intervention(4 weeks)
研究者
Peter Lemon
PhD
University of Western Ontario, Canada
