Perioperative Major Adverse Cardiac Events in high risk patients undergoing major non cardiac surgeries: how accurately does pro-BNP and cardiac Troponin T predict the occurrence of major adverse cardiac events?

Postgraduate Institute of Medical Education and Research Chandigarh0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年10月16日

试验速览

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•Patients with prior history of coronary artery disease will be defined as having any one of the following:
•i)Definite CAD as indicated by a previous history of MI, typical angina or ECG changes suggestive of previous MI without a documented history of MI
•ii)Patient who underwent coronary artery reperfusion therapy including previous fibrinolytic therapy, percutaneous coronary intervention and coronary angioplasty.
•Patient at risk of coronary artery disease will be defined as those with age 45 yr or older and had at least one of the following major cardiac risk factors34:
•1) Diabetes mellitus
•2) Peripheral artery disease (i.e. intermittent claudication or history of vascular surgery except arteriovenous shunt and vein-stripping procedures)
•3) History of hospitalization for congestive heart failure
•4) Renal insufficiency (defined as preoperative creatinine >150 µmol litre-1)
•5) History of cerebral vascular event
•6) Aortic valve stenosis (defined as aortic valve area <1 cm2)
•7) Atrial fibrillation
•8) Moderate or poor left ventricular function (defined as left ventricular ejection fraction <55%)

•Patients will be excluded from study participation if they had no signed informed consent.

发起方

Postgraduate Institute of Medical Education and Research Chandigarh