Ventilator Weaning Practices in Patients Intubated for Guillain-Barré Syndrome or Myasthenia Gravis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 800
- 试验地点
- 1
- 主要终点
- The proportion of patients with prolonged weaning
研究概览
简要总结
Guillain-Barré syndrome and myasthenia gravis are two neuromuscular diseases that are commonly managed in ICUs that may require different weaning protocols. To date, no study has compared weaning modalities from mechanical ventilation in patients with these two diseases. Our objective was to assess and compare for ventilator weaning modalities between patients mechanically ventilated for Guillain-Barré syndrome or for myasthenia gravis in a large-scale multicenter study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients mechanically ventilated for at least 48 hours for Guillain-Barré syndrome or myasthenia gravis -
排除标准
- •Patients mechanically ventilated less than 48h or intubated for another reason than the neuromuscular disease.
结局指标
主要结局
The proportion of patients with prolonged weaning
时间窗: 7 days after the initial separation attempt from the ventilator
Prolonged weaning defined as still being under mechanical ventilation at least 7 days after the initial separation attempt from the ventilator
次要结局
未报告次要终点
