Age of Blood Evaluation, resuscitation in the critically ill - ABLE

Sanquin Bloedbank0 个研究点目标入组 450 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•1) The need of a first red cell unit transfusion in the first 7 days of ICU admittance (or in the emergency department after admission to the ICU was requested by an intensivist),
•2) an anticipated length of invasive and/or non-invasive mechanical ventilation of at least 48 hours once enrolled, as estimated by the attending physician.
•3) age >18 years

•Exclusion criteria ABLE:
•- Age below 18
•- Suspection (written or otherwise) of a previous red cell transfusion during the current admitance
•- Preexisting terminal illness with a life expectancy < 3 months
•- Patients who undergo routine elective ( cardiothoracic) surgery during the same hospitalisation
•- Patients who have treatment restrictions other then a DNR at the time of randomization
•- Patients who are declared braindead
•- Patients who have moral or religious reasons to refuse a red cell transfusion
•- Patients who received autologous blood
•- Patients who are included in an other study
•- Patients whose physician refuses to include him/her
•- Patients who have previously participated in the ABLE study
•- Patients who received more then one unit of uncross-matched blood
•- When supplying the right randomised red cell unit causes logistical problems

发起方

Sanquin Bloedbank